Lymphomas of the Skin

Cutaneous lymphomas are rare cancers of white blood cells (lymphocytes) that begin in the skin rather than the lymph nodes. The two main groups — T-cell and B-cell lymphomas of the skin — behave differently and are treated differently, but most types grow slowly and respond well to treatment.
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About Skin Lymphoma Treatment Services:

Skin lymphomas are masters of disguise, often mimicking eczema, psoriasis, or a stubborn rash for years before diagnosis. At Charleston Dermatology, our physicians and providers evaluate persistent, treatment-resistant patches, plaques, and nodules with skin biopsies and specialized testing to identify the exact lymphoma type.

The subtype matters enormously—it determines the outlook and the entire treatment approach. Treatment plans are built around your specific diagnosis and stage, and may include skin-directed therapies like prescription topicals, phototherapy, and radiation, or systemic treatment coordinated with oncology for more advanced disease.

Most patients with early-stage skin lymphoma live full, normal lifespans. Schedule a visit and let our team give you a clear diagnosis and a clear plan.

Frequently Asked Questions

They are cancers in which lymphocytes — immune cells — grow abnormally within the skin. Cutaneous T-cell lymphomas (like mycosis fungoides) are the most common group and typically appear as scaly patches or plaques. Cutaneous B-cell lymphomas usually appear as firm pink or violet nodules. Both are rare, and neither is contagious.

The cause is unknown in most cases. Skin lymphomas are not inherited in a predictable pattern and are not linked to anything you did. They’re most often diagnosed in adults over 50, and men are affected somewhat more often than women.

Early-stage disease is usually managed with treatments directed at the skin itself: topical prescriptions, light therapy, or localized radiation. More advanced disease may involve oral or infused medications managed together with an oncologist. Because these are chronic conditions, ongoing monitoring is part of every plan — and many patients keep their disease well controlled for decades.

Our Specialists

Adam Sperduto, MD
Roger Sullivan, MD
Lee Yarbrough, MD
Ashley Allen, MD
Megan Hohenberger, MD