Mohs Surgery for Atypical Fibroxanthoma

Atypical fibroxanthoma (AFX) is an uncommon skin cancer of sun-damaged skin, usually on the head and neck of older adults. Mohs micrographic surgery is a preferred treatment because it confirms complete removal in areas where tissue is at a premium.
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About Mohs Surgery for Atypical Fibroxanthoma

AFX tends to appear exactly where surgical precision matters most—the scalp, ears, and face—often in skin already thinned by decades of sun.

At Charleston Dermatology, our surgeons treat AFX with Mohs surgery, examining the complete margin under the microscope during your visit. That margin control matters for AFX, which can extend beyond what’s visible on the surface and recurs more often when removal is incomplete.

Because the tumor is removed layer by layer only where cancer cells remain, healthy tissue on the scalp, ear, or face is preserved for the repair. With complete removal, the outlook for AFX is excellent, and follow-up skin exams round out the plan. Schedule a consultation and we’ll map out your treatment.

Frequently Asked Questions

AFX usually occurs on the head and neck, where sparing healthy tissue makes a real cosmetic and functional difference, and studies show lower recurrence rates with Mohs than with standard excision. Checking 100% of the margin also matters for a tumor that can send extensions beyond its visible edge.

Very good. AFX rarely spreads beyond the skin, and complete removal with clear margins is usually curative. Recurrence after Mohs is uncommon. Your surgeon will recommend a follow-up schedule, both to watch the surgical site and because sun-damaged skin that produced one cancer can produce others.

Mohs for AFX is an outpatient procedure done under local anesthetic. Plan for several hours: removal, on-site microscopic examination while you wait, additional stages only if needed, and repair of the site the same day. Most patients return to light activity the next day, with sutures typically removed in one to two weeks.

Our Specialists

Adam Sperduto, MD
Roger Sullivan, MD
Lee Yarbrough, MD
Ashley Allen, MD
Megan Hohenberger, MD