Cutaneous T-Cell Lymphoma

Cutaneous T-cell lymphoma (CTCL) is a rare cancer of the immune system’s T-cells that shows up first in the skin, often as persistent scaly patches or plaques that can look like eczema or psoriasis for years.
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About Cutaneous T-Cell Lymphoma Treatment Services

A “stubborn rash” that never fully responds to treatment deserves a second look, because CTCL is one of dermatology’s great imitators.

At Charleston Dermatology, our physicians and providers evaluate persistent, treatment-resistant patches with skin biopsies, sometimes more than one over time, since early CTCL can be difficult to confirm. Getting the diagnosis right—and staging it accurately—shapes everything that follows.

Treatment plans are built around your stage and symptoms, and may include prescription topical therapies, phototherapy (light treatment), radiation, or systemic medications coordinated with oncology for more advanced disease. Most patients diagnosed early live normal lifespans with well-controlled disease. Schedule a visit and let our team take a closer look.

Frequently Asked Questions

CTCL is a group of rare lymphomas in which cancerous T-cells collect in the skin. The most common type, mycosis fungoides, usually begins as flat, scaly, discolored patches on areas the sun doesn’t reach, like the buttocks, trunk, and thighs. It typically progresses slowly over years.

The cause is unknown. CTCL is not inherited in a predictable way, is not contagious, and is not caused by anything you did. It’s most often diagnosed in adults over 50 and is somewhat more common in men.

Early-stage disease is often managed with skin-directed treatments: prescription topical steroids, nitrogen mustard gel, or phototherapy. More advanced disease may call for radiation or systemic therapies managed together with an oncologist. Because CTCL is chronic, ongoing follow-up and a long-term relationship with your care team are central to treatment.

Our Specialists

Adam Sperduto, MD
Roger Sullivan, MD
Lee Yarbrough, MD
Ashley Allen, MD
Megan Hohenberger, MD